Microcalcifications Detection Using Image Processing

Abstract

Breast cancer is the most common cause of death in women and the second leading cause of cancer deaths worldwide. Primary prevention in the early stages of the disease becomes complex as the causes remain almost unknown. However, some typical signatures of this disease, such as masses and microcalcifications appearing on mammograms, can be used to improve early diagnostic techniques, which is critical for women’s quality of life. X-ray mammography is the main test used for screening and early diagnosis, and its analysis and processing are the keys to improving breast cancer prognosis. In this work, an effective methodology to detect microcalcifications in digitized mammograms is presented. This methodology is based on the synergy of image processing, pattern recognition and artificial intelligence. The methodology consists in four stages: image selection, image enhancement and feature extraction based on mathematical morphology operations applying coordinate logic filters, image segmentation based on partitional clustering methods such as k-means and self organizing maps and finally a classifier such as an artificial metaplasticity multilayer perceptron. The proposed system constitutes a promising approach for the detection of Microcalcifications. The experimental results show that the proposed methodology can locate Microcalcifications in an efficient way. The best values obtained in the experimental results are: accuracy 99.93% and specificity 99.95%, These results are very competitive with those reported in the state of the art.